Reserpine FDA Link

An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.

Also Known As:

Serpasil; Serpivite; Raunervil; Raupasil; Rausedil; Rausedyl; V-Serp; V Serp; Yohimban-16-carboxylic acid, 11,17- dimethoxy- 18- ((3,4,5- trimethoxybenzoyl)oxy)- , methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-

Pharmalogical Action Categories:

Adrenergic Uptake Inhibitors
Antihypertensive Agents
Antipsychotic Agents

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Indole Alkaloids: 200
    - Secologanin Tryptamine Alkaloids: 81
      - Yohimbine: 901
        Reserpine: 2387
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indole Alkaloids: 200
        Secologanin Tryptamine Alkaloids: 81
        Yohimbine: 901
        Reserpine: 2387
    - Indolizines: 3
      - Indolizidines: 2
        Indole Alkaloids: 200
        Secologanin Tryptamine Alkaloids: 81
        Yohimbine: 901
        Reserpine: 2387

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Disease

Drug/Important Bio-Agent (IBA)